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Wednesday, 9th December 2009

Unexpected success

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Published Date: 11 September 2007
ALL this week, The Scotsman is profiling some of the greatest Scottish inventors - and giving you the chance to vote for the one you judge has made the greatest contribution to the modern world.
Choose from theorists such as James Clerk Maxwell, pioneers including James Watt and Alexander Graham Bell, or modern heroes such as James Black and Ian Donald, whose contributions to medicine are still saving lives today.

We will profile our sho
rtlist of 17, with big names such as TV trailblazer John Logie Baird and penicillin pioneer Sir Alexander Fleming, and tell the stories of some less well-known inventors, including James Goodfellow, who gave us the modern cash machine.

Follow the inventors in The Scotsman until next Saturday and vote using the information below.

Name: Alexander Fleming


Born: 6 August, 1881, Darvel, near Ayrshire
Died: 11 March, 1955, Chelsea, London
Claim to fame: Fleming was one of three scientists given the Nobel Prize for the discovery of penicillin.

IT WAS watching the agony of soldiers dying of septicaemia in the First World War which spurred Scottish doctor Alexander Fleming to become a bacteriologist.

Fleming was a brilliant researcher who discovered the body's antiseptic lysozyme and was made professor of bacteriology at St Mary's Hospital in London.

But it was an accidental discovery which was to make him one of the most famous scientists in the world.

In 1928 Fleming, who was notoriously untidy, left a petri dish smeared with staphylococcus lying out in his laboratory while he went on holiday for two weeks.

When he returned the Professor discovered the plate had been contaminated with mould and realised the germ was absent from the area around the spreading fungus.

Fleming preserved the mould-covered petri dish, realising that the inhibiting power of the fungus revealed its potential as the basis of a new drug.

Later he was to address young scientists about the importance of keeping an eye for the unexpected.

He said: "I have been trying to point out that in our lives chance may have an astonishing influence and, if I may offer advice to the young laboratory worker, it would be this - never to neglect an extraordinary appearance or happening."

Fleming discovered penicillin was effective against the pathogens which caused pneumonia, gonorrhoea and meningitis. However, he lacked the expertise to create a form of penicillin which worked in practice.

But in 1939 a specimen of Fleming's penicillin reached a team of scientists at Oxford University, including Australian biochemist Howard Florey and German scientist Ernst Boris Chain.

Finally Fleming's insight could be put to use as Florey and Chain worked out how to purify penicillin and successfully demonstrated how a dose of the new drug could cure mice which had been injected with lethal doses of bacteria.

When Fleming heard of their work he immediately made plans to visit them in Oxford to the astonishment of Chain, who was said to have remarked: "Good God, I thought he was dead."

With the Second World War looming it was more important than ever to find ways of fighting infection, and the Oxford team worked day and night to work out the process by which penicillin could be manufactured and used in the field. By the end of the Second World War millions of lives had been saved by putting Fleming's theory into practice.

Almost overnight a host of diseases which had once meant certain death, which included pneumonia, syphilis, gonorrhoea, diphtheria and scarlet fever, and many wound and childbirth infections had become treatable.

Fleming, along with Florey and Chain, was awarded the Nobel Prize in 1945 but, while the Oxford scientists shunned the publicity, the Scottish scientist embraced the limelight and became an international hero.

The tweed-suited Scottish doctor became friends with Marlene Dietrich, who believed he had saved two members of her family. She read his horoscope and he gave her a slide of penicillin in return.

Singer Josephine Baker dedicated a song to Fleming in a nightclub in Barcelona, Spanish bullfighters knelt in his honour and he became friends with Douglas Fairbanks jnr and Eleanor Roosevelt.

When wild stories began to circulate about how he had saved Winston Churchill from drowning as a boy Fleming said it was "a wondrous fable" and spoke of "the Fleming myth".

Despite his new-found fame, Fleming continued to research the possibilities of penicillin and he was one of the first to realised its limitations, realising that overuse and inadequate doses could lead to the development of antibiotic-resistant bacteria.

Before his death Fleming was made a Baron for his role in the invention of a type of drug which transformed medicine forever.

In 2000 a Swedish magazine named penicillin the "Discovery of the Century", and estimated the invention of antibiotics had led to 200 million lives being saved.

As Fleming himself succinctly observed: "One sometimes finds what one is not looking for."

Name: Kirkpatrick Macmillan


Born: 2 September, 1812, Keir, Dumfries and Galloway
Died: 26 January 1878, Keir
Claim to fame: Inventor of the pedal bicycle

THERE are those who dispute the claim that Kirkpatrick Macmillan was the first person who thought of adding pedals to a bicycle. But others say it was only the natural modesty of the blacksmith from Dumfriesshire which prevented him from taking more credit or profiting from his invention.

And the earliest example of a bicycle in the Science Museum in London is the one made by Macmillan by welding pedals to the two-wheeled "hobby horse" developed by Baron von Drais.

Macmillan was in his twenties and working as a blacksmith for the Duke of Buccleuch when he first spotted a man riding on a hobby horse and decided to build his own. But the young man was disappointed by the lack of speed as he pushed the two-wheeled chariot along the bumpy back roads with his feet. He hit upon the idea of using a system of cranks and pedals to propel the machine and manufactured a piece of equipment at the family smithy in Courthill.

It was a heavy device, which used stiff rods, rather than a chain, to connect the wheels with the pedals, but Macmillan, who finished his prototype in 1839, was delighted with the invention.

He used his bicycle to take regular trips to Dumfries, 14 miles from the family house, and, in June 1842, set out on a two-day journey to Glasgow - a distance of 70 miles. During his visit to the big city, Macmillan earned himself one of the world's first fines for speeding after his contraption knocked over a little girl in the street.

Despite his great adventures as a cyclist Macmillan was a man who was content with his lot and never took the trouble to patent his design or exploit it for profit. He did make bicycles for other people, for a price of £7 each, but it was Gavin Dalzell, of Lesmahagow, who saw the potential in the design and became the world's first commercial manufacturer of bicycles.

For many years Dalzell, who began making his own cycles in 1846, was widely thought of as the inventor of the bicycle, but Macmillan's contribution emerged later, after his death.

Other inventors such as John Kemp Starley, Henry Lawson and the Michaux family added refinements to the design, adding a chain drive and gears. And it was the French in the 1860s who were really responsible for making cycling popular.

But few inventors can have derived as much pleasure from their creations as Kirkpatrick Macmillan did from his bicycle - which a 2005 survey declared the greatest British invention of all time. As a plaque on the family smithy in Kirkhall reads: "He builded better than he knew."

Name: William Thomson, Lord Kelvin


Born: 26 June, 1824, Belfast
Died: 17 December, 1907
Claim to fame: Father of thermodynamics and creator of the Kelvin scale

BORN in Belfast, Thomson moved to Glasgow at the age of ten and immediately enrolled at the university where his father was the professor of mathematics. Schooled largely by his father, Thomson was an academic prodigy who rose to become one of the most hard-working and influential physicists of his day and who was given the chair of natural philosophy at the age of 22.

He corresponded with prominent physicists, including James Joule and laid the foundation for thermodynamics with his theories of "statical" and "dynamical" energy - or what we now call potential and kinetic energy.

He proposed an absolute temperature scale - named the Kelvin scale in his honour - which places the coldest temperature in the Universe at zero degrees Kelvin.

Thomson was elected a member of the Royal Society at the age of just 27 and published 660 scientific papers during his career, the first at the age of 16. His views about the age of the earth brought him into conflict with Thomas Huxley and Charles Darwin, who called him an "odious spectre".

Thomson argued that the Earth was just 100 million years old, based on his calculations for how long it had taken to cool to its current temperature. This would not have been sufficient time for evolution to occur.

Thomson was vilified for his attempts to counter the theory of evolution, but his arguments were based on a wish for scientific rigour rather than any misplaced attempt to defend Christianity.

Current theories suggest the earth is 4,600 million years old - Thomson's calculations failed to take into account the counteractive effect of radiation, which was unknown at the time he was working.

Thomson is today regarded as one of the founding fathers of thermodynamics, but during his lifetime he was known as much for his role in the application of scientific ideas as the development of theory.

He was a member of the board of directors of the Atlantic Telegraph Company, whose aim was to lay a telegraph cable along the 3,000-mile seabed between Europe and North America.

Thomson spent months at sea working on the project, which finally succeeded in 1866 at the fifth attempt. The Times called it "the most wonderful achievement of this victorious century". Thomson was knighted for his part and became a public figure.

HOW TO ENTER

ONLINE: log onto www.scotsman.com/scotlandsgreatestinventor and follow the instructions on how to vote.

E-MAIL: E-mail greatinventors@scotsman.com. This is the only way of voting for inventors not on our list or adding comments.

TEXT: text the word INVENTOR followed by a space, then the numeric code of the inventor you would like to vote for followed by a space - then your name, a space, then your postcode. Send to 81800 (charged at standard network rate
third parties.

1001 John Logie BAIRD
1002 Alexander Graham BELL
1003 James BLACK
1004 Ian DONALD
1005 John Boyd DUNLOP
1006 Alexander FLEMING
1007 James GOODFELLOW
1008 Lord KELVIN
1009 Charles MACINTOSH
1010 Kirkpatrick MACMILLAN
1011 James Clerk MAXWELL
1012William MURDOCH
1013 James Young SIMPSON
1014 Robert WATSON-WATT
1015 James WATT
1016 Ian WILMUT
1017 James 'Paraffin' YOUNG

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Page 1 of 1

 
1

Guga II,

Rockall 11/09/2007 01:38:53

Howard Florey was an Australian, not an Austrian. It was Florey that developed penicillin as a drug.

Are the Hootsmon subbies have a night off again?

2

W Smith,

Middle East 11/09/2007 03:22:44

A wee question for the Salmond-istas.

How many of these great Scottish inventors / scientists / engineers thought the union flag was nothing more than a "Butchers Apron"?

3

AMNo2tiredofmoaningtothemoderator,

11/09/2007 05:21:24

Poor poor sad W Smith. Difficult to embrace any pride in your own people eh?

4

donald a,

weegieland 11/09/2007 05:44:42

"A wee question for the Salmond-istas.
How many of these great Scottish inventors / scientists / engineers thought the union flag was nothing more than a "Butchers Apron"

So you are proud of British bloodbaths?

5

eddylongshanks,

11/09/2007 06:40:33

donald - so you are proud of Scottish involvement in them ?

6

fred bloggs,

11/09/2007 06:42:23

Penicillin was not 'invented'; it was discovered.

7

fred bloggs,

11/09/2007 06:50:11

James Clerk-Maxwell towers above these people (like Fleming and Baird, both of whose contributions have been greatly exagerrated)

8

Boy Wonder,

11/09/2007 06:58:35

So ... who compiled the shortlist?? Who was it felt themselves QUALIFIED enough to select this smattering of scientific heroes?? A committee? An editor??

I won't be voting because lists like these are always subjective ... and there's probably some inventor or discoverer been left off the list that many people think should have been on it. Just because TV does their "most popular" list doesn't mean everybody should jump on the bandwagon.

I am proud of each and everyone of my fellow Scots, past and present, who have contributed to the wealth of knowledge about the way our universe works!

Where's Alexander WOOD for instance, who invented the hypodermic syringe, or James SYME, who developed Plastic Surgery? Or George CLEGHORN, discoverer of quinine?

We have always been a nation of inventors and discoverers ... and as a boast of the inventive ingenuity and practical nature of the Scots there is an old saying, ' It was an Englishman who received the credit for inventing the toilet seat - but it was a Scotsman who came up with the idea of cutting a hole in the middle of it !' :)

9

AMNo2tiredofmoaningtothemoderator,

11/09/2007 07:30:03

Our greatest inventor was the chap who came up with the brainwave of putting all our nations achievements on a tea towel.

10

AMNo2tiredofmoaningtothemoderator,

11/09/2007 08:49:38

It's a great pity that The Scotsman don't read their own archives when putting these pieces together.

To include Dunlop without considering Robert William Thompson is daft.

'The Scotsman described this application of vulcanised India-rubber to the wheels of road steamers as "the greatest step which had ever been made in the use of steam on common roads".'

http://en.wikipedia.org/wiki/Robert_William_Thomson

As is the exclusion of William Murdoch, notable for inventing a wooden hat and the simple matter of gas lighting.

http://en.wikipedia.org/wiki/William_Murdoch

11

Findlay Thompson,

Edinburgh 11/09/2007 09:57:08

Watson-Watt.

We have a free world thanks to him.

12

Saltire,

China 11/09/2007 10:08:12

Instead of this shortlist why do we not just get everybody to contribute the names of their favourite inventors/discoverers?
Then the Scotsman can publish the full list - now there would be a list to be proud of!!!!

13

Dougie Douglas,

Brisbane 11/09/2007 10:39:03

In the interest of balance and to stop us Scots getting too ahead of ourselves perhaps AM2 could go into his archives and produce the list of 'Great Yorkshire and Humberside Inventions'.

14

Dougie Douglas,

Brisbane 11/09/2007 10:40:21

W Smith

You didn't invent the cultural cringe but you certainly keep it alive with nonsense like post #2

15

Cadgers,

Perth 11/09/2007 12:48:53

What aboot John Muir?
#9 Agree BW I wouldn't trust the Hootsman to make a list of messages never mind one of this calibre.
LOL nearly posted Hoorsman :-)

16

Twitcher,

Aberdeen 11/09/2007 13:26:02

Jings........no-one thought include the deep fried Mars Bar. Was that invented or discovered?

17

Tarchin,

Lothian 11/09/2007 13:28:56

Is Ian Wilmut a Scot?
Why no mention of John Napier, discoverer of logarithms?
Why no mention of Thomas Telford who designed and developed many revolutionary civil engineering projects?

18

Haggislover,

11/09/2007 14:05:59

What rubbish, this whole idea of self importance we have because certain items were invented by Scots. Important inventions or discoveries are spread around the globe.

Thomas Edison, inventor of the light bulb was not a Scot, but without him we would be watching our TVs by candlelight.

19

Guga II,

Rockall 11/09/2007 14:13:57

#21 Tell that to Swan, the English inventor of the lightbulb.

20

Findlay Thompson,

A74 (M6)- Carlisle 11/09/2007 14:47:59

20. Very interesting point.

Thomas Telford was not an Inventor but an improver. He took existing designs & bettered them. You could say he alone was responsible for the first modern suspension bridge (Menai).

You could also mention that Architectural & Civil Engineering globally, advanced a century in his working lifetime!

21

AMNo2tiredofmoaningtothemoderator,

11/09/2007 15:03:20

#21 Haggisstalker

How odd you are, however without Scot William Kennedy Laurie Dickson we wouldn't be watching films made possible by Edison. Besides we could have continued to watch by gas light invented by Scot William Murdoch. Also I suppose if it weren't for Orcadian James Petrie Chalmers cinema as we know it wouldn't exist either.

Wha's like us, eh?

22

Haggislover,

11/09/2007 15:11:43

#22 The first electric light was made in 1800 by Humphry Davy, an English scientist. I only used Edison to make my little joke.

Actually if one person doesn't invent a particular item another right behind him will. Until the invention of the bow, people had to fling their arrows at their prey by sheer arm power.

Their are no inventions, only discoveries.

23

MtnKat,

11/09/2007 16:21:33

#2 Well, quite a few emigrated.

For all the squabbling here, it is still the least depressing article on offer today.
Do they save up all of the horrendous acts people perpetrate upon each other for Tuesday?

24

freedomfries,

11/09/2007 19:02:30

Well said #26. What a downer. Surely there's something positive happening out here.

25

WMSART,

EDNBURGH 11/09/2007 20:08:45

FRED BLOGS 7

CORRECT EVEN EIENSTIEN COULD NOT HAVE SUCCEEDED WITHOUT THE WORK OF MAXWELL

26

Maurice,

fife 12/09/2007 00:19:27

Who invented whisky???

27

Snowbird,

toronto 12/09/2007 14:27:43

What about MacAdam who invented roads????????

28

Dileas_sean,

California 12/09/2007 17:11:35

Why not change the names of a few streets in Scotland's major cities, and call them after the great inventors ? There is even a Dr Fleming Street in Cadiz, Spain. whilst Edinburgh is full of Georges and Princes etc. who did nothing for Scotland


 

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